Modular platform for biosensor assembly
Tumor markers are biological substances, usually proteins, that provide early indication of cancerous or benign tumors in the body.
View ArticleDeveloping a gel that mimics human breast for cancer research to reduce the...
Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and...
View ArticleScientists produce clearest-ever images of enzyme that plays key roles in...
An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.
View ArticleNuclear membrane repairs the 'dark matter' of DNA
Scientists have found a new function of the nuclear membrane, the envelope that encases and protects DNA in the nucleus of a cell - it fixes potentially fatal breaks in DNA strands.
View ArticleDiscovered: A cluster of 60 proteins that help cells move and feel
University of Manchester scientists have discovered a cluster of 60 proteins that allow the body's cells to react to their environment and communicate with each other.
View ArticleDNA 'building blocks' pave the way for improved drug delivery
DNA has been used as a 'molecular building block' to construct synthetic bio-inspired pores which will improve the way drugs are delivered and help advance the field of synthetic biology, according to...
View ArticleNew study using cryo-electron microscopy shows how potential drugs could...
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in atomic detail, the binding of a potential small molecule drug to a key protein in...
View ArticleResearchers find unique regulatory pattern that promotes essential cell function
Scientists and clinicians often encounter road blocks in designing specific treatments for diseases like cancer or developmental disorders because proteins that regulate cell functions through complex...
View ArticlePerforming cellular surgery with a laser-powered nanoblade
To study certain aspects of cells, researchers need the ability to take the innards out, manipulate them, and put them back. Options for this kind of work are limited, but researchers reporting May 10...
View ArticleMalignancy-associated gene network regulated by an RNA binding protein
If he ever gives a TED talk, Jeremy Sanford may have to come up with a better name for the protein he's been studying, which appears to play an important role in driving the proliferation and...
View ArticleIlluminating detection of deep cancers
To see right through something is to know its true intent—the same could be said to apply to biological tissues, especially tumors.
View ArticleSynthetic biology used to limit bacterial growth and coordinate drug release
Researchers at the University of California San Diego and the Massachusetts Institute of Technology (MIT) have come up with a strategy for using synthetic biology in therapeutics. The approach enables...
View ArticleBlocking a human branched DNA enzyme offers new ways of targeting a crucial...
An international team of scientists has discovered how compounds block flap endonuclease 1 (FEN1) - a crucial enzyme class in the DNA damage response and potential target for cancer treatment.
View ArticleHow cell nuclei squeeze into tight spaces
As cells move throughout our bodies, they often have to squeeze through tight nooks and crannies in their environment, reliably springing back to their original shape. The structures involved in this...
View ArticleIsraeli scientists say they can block melanoma spread
Israeli scientists have uncovered how the most severe form of skin cancer spreads to other organs in a discovery that could revolutionise treatment of the disease, they said Tuesday.
View ArticleNASA astronaut wears spacesuit painted by kids with cancer
Some childhood cancer patients will chat Friday with an astronaut aboard the International Space Station wearing a hand-painted spacesuit they helped decorate.
View ArticlePortable biological factories create pharmaceuticals
Pellets made from freeze-dried molecular components make it possible to "just add water" to create diverse compounds without the need for refrigeration. This portable and inexpensive platform, intended...
View ArticleNew advance in RNA studies holds out hope for cancer drug development
An international research team led by the University of Leicester has made a breakthrough advance that could pave a new route for the development of anti-cancer drugs.
View ArticleGene "bookmarking" regulates the fate of stem cells
A protein that stays attached on chromosomes during cell division plays a critical role in determining the type of cell that stem cells can become. The discovery, made by EPFL scientists, has...
View Article'Rewired' cells show promise for targeted cancer therapy
A major challenge in truly targeted cancer therapy is cancer's suppression of the immune system. Northwestern University synthetic biologists now have developed a general method for "rewiring" immune...
View ArticleNew kit helps researchers make sense of mass cytometry datasets to uncover...
A new software package offers easier analysis and interpretation of experiments that use mass cytometry, a sophisticated method for determining the properties of cells. The tool—called cytofkit—enables...
View ArticleVitamins and aminoacids regulate stem cell biology
An International Reserach Team coordinated by Igb-Cnr has discovered a key role of vitamins and amino acids in pluripotent stem cells. The research is published in Stem Cell Reports, and may provide...
View ArticleScientists unlock secret of chromosome copier
University of Dundee scientists have solved a mystery concerning one of the most fundamental processes in cell biology, in a new discovery that they hope may help to tackle cancer one day.
View ArticleA CLOUD of possibilities: Finding new therapies by combining drugs
The CeMM Library of Unique Drugs (CLOUD) is the first condensed set of FDA-approved drugs representing all clinical compounds. Its potential was shown in a combinatorial high throughput screen at the...
View ArticleHow the optics of soap bubbles may help us understand the mechanics of immune...
Scientists at the University of St Andrews have developed an advanced new microscopy technique that could revolutionise our understanding of how immune and cancer cells find their way through the body.
View ArticleBiosensors light up cellular signaling processes
Researchers at the University of California, Riverside have converted a naturally occurring fluorescent protein from corals into a biosensor that can be used to monitor the cellular thioredoxin (Trx)...
View ArticlePhysicists develop new tool that could improve cancer research
University of Arkansas physicists have developed a new way for quantifying data from microscopic observations that could help scientists better study how cancer cells respond to treatment, among other...
View ArticleResearchers discover new targets for approved cancer drug
Developing new drugs to treat cancer can be a painstaking process taking over a decade from start to Food and Drug Administration approval. Scientists are trying to develop innovative strategies to...
View ArticleNew machine learning system can automatically identify shapes of red blood cells
Using a computational approach known as deep learning, scientists have developed a new system to classify the shapes of red blood cells in a patient's blood. The findings, published in PLOS...
View ArticleIt's mathematically impossible to beat aging, scientists say
Aging is a natural part of life, but that hasn't stopped people from embarking on efforts to stop the process.
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